What few doctors understand are the unique mechanisms by which metformin can prevent and even help treat certain cancers. The ability of metformin to help facilitate weight loss has long been known. In 2010 alone, scientists at top-ranked institutions made landmark discoveries that broaden its use to combat degenerative disease. The Drug Virtually Everyone Should Ask their Doctor About With each passing year, fresh scientific evidence emerges to vindicate Life Extensions contention that aging humans can derive enormous benefit from an antidiabetic drug called metformin. The Drug Everyone Should Ask Their Doctor About. Chromium, as compared to placebo, reduced food intake, hunger levels, and fat cravings and decreased A double-blind placebo-controlled study in 2008 randomly assigned 42 overweight adult women with carbohydrate cravings to receive chromium or placebo for 8 weeks. There is a lack of good studies on chromium for weight loss. Insulin, however, is also required to drive serotonin into the brain and it is though that chromium affects both serotonin and dopamine, which may explain its postiive effects on mood. We now know that the essential mineral increases insulin binding, increases the number of insulin receptors and also increases insulin effectiveness all of which lead to improved glucose transport into muscle, fat and liver tissue, and therefore better glucose control. Chromiums role in insulin regulation was first proven in the 1970s. While there is no RDA as such the US National Academoy of Sciences suggest we need an intake between 50 and 200g. In addition to the problem of low consumption due to eating refined and processed foods (white flour has 98% of its chromium removed), it has been shown that typical western diets high in refined food such as white bread, cakes, sweets and biscuits increase chromium losses because it is used up in processing sugar. The average intake is thought to be in the region of 28-35g. Despite being naturally present in foods such as beer, whole grains, cheese, liver, and meat, the typical intake in a western diet is much lower than the recommended daily requirement of 50-200g/day (micrograms per day). Supplementation has been shown to help stabilise blood sugar and thus helps diabetes, control weight and appetite, improve mood and binge eating. Chromium is a non-toxic mineral, essential for carbohydrate, protein and fat metabolism.
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